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Triamterene is a member of the drug class potassium-sparing diuretics. Triamterene, one of the ingredients of Dyazide, helps to minimize the potassium loss that can be caused by the other component, hydrochlorothiazide. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis, such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (eg, spironolactone, triamterene, amiloride) (see OVERDOSAGE). htmlTriamterene is generally well-tolerated, especially in patients with adequate urine output. Triamterene may pass into breast milk and could cause harm to a nursing baby.

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